Patient Derived Xenograft Model Market Size To Reach USD 0.759 Billion, With a CAGR 13.30% by 2032 – Report by MRFR
Research Reports
Oct 11, 2023
Patient Derived Xenograft Model Market Research Report: Information by Tumor Type (Lung Cancer, Pancreatic Cancer, Prostate Cancer, Breast Cancer and Other Cancer), by Model Type (Mice and Rats), by End-User (Pharmaceutical And Biopharmaceutical Companies, Academic & Research Institutes and CROs & CDMOs) And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2032
According to MRFR analysis, the global Patient Derived Xenograft Model Market is expected to register a CAGR of 13.30% from 2023 to 2032 and hold a value of over USD 0.759 Billion by 2032.
Patient-derived xenograft models, often referred to as PDX models, involve transplanting cancerous tissue or cells from patients directly into immunodeficient mice. This approach preserves the unique genetic and histological characteristics of the patient’s tumor, thus making PDX models invaluable for cancer research and personalized medicine. PDX models serve as a more accurate representation of human tumors than traditional cell lines, enabling researchers to study the disease’s complexity and response to treatments in a clinically relevant context.
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The patient-derived xenograft (PDX) model market is anticipated to experience rapid expansion in the coming years, revolutionizing preclinical cancer research and personalized medicine. Patient-derived xenograft (PDX) models are a valuable tool in biomedical research, wherein immunodeficient mice are implanted with tumor tissue obtained from patients. These models effectively mimic the intricate nature and diverse characteristics of real cancers, hence facilitating more precise drug testing and the advancement of therapeutic interventions.
Segmentation
Tumor Type Insight
In 2022, the market was predominantly influenced by the breast cancer category. The therapeutic paradigm for certain subtypes of breast cancer has undergone significant transformations as a result of the introduction of targeted therapies such as HER2-targeted drugs and hormone therapy.
Model Type Insights
In the fiscal year of 2022, the category of mice had the highest revenue generation. Mice are frequently employed as hosts for patient tumor tissues because to their biological relevance and somewhat stronger genetic resemblance to humans compared to other animal models.
End-use Insight
In 2022, the market was predominantly led by the Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs) sector. When evaluating the financial implications, it is essential to compare the expenses associated with outsourcing PDX model-related research to Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs) against the costs of establishing and maintaining in-house expertise.
Key Players
Some of the top market players are Charles River Laboratories, The Jackson Laboratory, Crown Bioscience, Altogen Labs, Envigo, WuXi AppTec, Oncodesign, Hera Biolabs, XenTech, Abnova Corp.
Regional Analysis
The North American region hosts a substantial pharmaceutical industry, with a predominant presence in the United States. The need for patient-derived xenograft (PDX) models mostly stems from this segment of the economy. Pharmaceutical companies in North America rely on PDX models for their exceptional ability to accurately replicate human tumor responses, owing to the continuous need for innovative treatment alternatives. This fosters the establishment of research collaborations and cooperation with academic institutions, hence facilitating the expansion of the market for patient-derived xenograft (PDX) models.
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The European market for patient-derived xenograft models holds the second-largest market share. The spread of the PDX model in Europe is primarily propelled by multinational collaboration. European nations actively endorse and facilitate cross-institutional collaboration, hence fostering significant exchange of information and pooling of resources for research including the PDX model. The prevalent culture of collaboration fosters a dynamic research environment in which the flow of ideas and information is openly facilitated, hence expediting the advancement of PDX model technology and its practical applications.
The market for Asia-Pacific Patient Derived Xenograft Models is projected to exhibit the highest compound annual growth rate (CAGR) during the years 2023 and 2032. The significant growth of the biotechnology sector in the Asia-Pacific region has played a pivotal role in driving the expansion of the PDX model market in this area. Several countries, such as China, Japan, and South Korea, have made substantial expenditures in the development of medication and research in the field of life sciences. The emergence of biotechnology has rendered PDX models indispensable in the realm of preclinical drug testing and cancer research.
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